Laboratory of Metabolism, Inflammation and Diseases
Drug Discovery Center at the School of Chemical Biology & Biotechnology

Zhiping Liu

Zhiping Liu, Ph.D  

Associate professor

Tel: +86-755-8616-0880; +86-755-2153-9221 Email: liuzp.sz@pku.edu.cn; zhiping0414@163.com

EDUCATION & WORKING EXPERIENCES
11/2017-Present: Associate Professor, Peking University Shenzhen Graduate School, Shenzhen, China

11/2014-11/2017: Visiting Fellow, Medical College of Georgia, Augusta, Georgia, USA

9/2014-06/2017: Postdoc Fellow, Peking University Shenzhen Graduate School, Shenzhen, China

09/2009-06/2014: Ph.D., Sun Yat-sen University (SYSU), Guangzhou, Canton, China

09/2005-07/2009: B.S., Sun Yat-sen University (SYSU), Guangzhou, Canton, China

RESEARCH INTREST:
Cardiovascular diseases, vascular biology, cellular metabolism, epigenetic regulation, inflammation, pharmacology, phytochemicals, natural product.
AWARDS & HONORS:
2018      PVD Travel Award for Young Investigators, 2018 Scientific Sessions (ATVB/PVD) in San   Francisco, California, USA

C2018       ELSEVIER, 《Pharmacological Research》Outstanding Contribution in Reviewing Award

2015      Second prize of Young Outstanding Paper Award of the 7th Academic Conference of Guangdong Pharmacological Society, China

2014      First prize of Outstanding Young Researchers of 5th National Pharmacy Graduate Student Forum, China

2013     "Zhi Xin” Graduate Scholarship, Sun Yat-sen University (SYSU)

2011      Excellent Graduate Scholarship, Sun Yat-sen University (SYSU)

2010      Excellent Graduate Scholarship, Sun Yat-sen University (SYSU)

REPRESENTATIVE PUBLICATIONS (#1co-first author, *co-first author)
1. Wang L, Cao Y, Gorshkov B, Zhou Y, Yang Q, Xu J, Ma Q, Zhang X, Wang J, Mao X, Zeng X, Verin A, Hong M, Liu Z*, Huo Y*. Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS induced endotoxemia. Pharmacol Res. 2019, DOI: 10.1016/j.phrs.2019.104292.
2. Zhou Y, Zeng X, Li G, Yang Q, Xu J, Zhang M, Mao X, Zhang X, Cao Y, Wang L, Xu Y, Wang Y, Xu Z, Wu C, Chen JF, Hoda MN, Liu Z*, Hong M*, Huo Y*. Inactivation of endothelial adenosine receptor 2A protects mice from cerebral ischemia-induced brain injury. Br J Pharmacol. 2019, doi: 10.1111/bph.14673.
3.Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton DJ, Weintraub NL, Caldwell RB, Zhang W, Wu C, Liu XL, Chen JF, Ahmad A, Ismail KD, Mohamed AS, Li Q, Jiang X, Sun Y, Sodhi A, Smith L, Hong M*, Huo Y*. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis. Nat Commun. 2017, 19;8(1):584.
4.Liu Z, Wang J, Huang X, Li Z, Liu P*. Deletion of SIRT6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice. Transl Res. 2016, 172:18-29.e2.
5.Liu Z#1, Xu S#1, Huang X, Wang J, Gao S, Li H, Zhou C, Ye J, Chen S, Jin ZG and Liu P*. Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in Apolipoprotein E-Deficient Mice: role of LOX-1. Br J Pharmacol. 2015, 172(23):5661-75.
6.Tian K#1, Liu Z#1, Wang J#1, Xu S, You T and Liu P*. Sirtuin-6 inhibits cardiac fibroblasts differentiation into myofibroblasts via inactivation of nuclear factor kappaB signaling. Transl Res. 2015;165:374-86.
7.Liu Z, Wang J, Huang E, Gao S, Li H, Lu J, Tian K, Little PJ, Shen X, Xu S, Liu P*. Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of haem oxygenase-1. J Lipid Res. 2014, 55:201-213.
8.Xu S#1, Liu Z#1, Liu P*. Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis. Int J Cardiol. 2014, 172:313-317.
9.Wang J#1, Liu Z#1, Feng X, Gao S, Xu S and Liu P*. Tumor suppressor gene ING3 induces cardiomyocyte hypertrophy via inhibition of AMPK and activation of p38 MAPK signaling. Arch Biochem Biophys. 2014, 562:22-30.
10.Xu S#1, Liu Z#1, Huang Y, Le K, Tang F, Huang H, Ogura S, Little PJ, Shen X, Liu P*. Tanshinone IIA Inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-kappa B activation. Transl Res, 2012, 160 (2):114-24.