Zhao Group
School of Chemical Biology & Biotechnology

Congratulations to Jingyi Zhao for his paper published on JACS

时间:2013-05-15

Congratulations to Jingyi Zhao for his paper published on JACS. Recently, Prof. Jing Zhao and Prof. Peng Chen in PKU CCME have developed a photoactivable firefly luciferase based on photocaged unnatural amino acid. They replaced an important lysine residue with a genetically encoded photocaged lysine analog that would block the substrate binding in the enzyme's active site, and restore the activity of the luciferase with a low does UV laser. This work is published on JACS, named <Mechanism-Based Design of a Photoactivatable Firefly Luciferase>.

赵静一

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http://pubs.acs.org/doi/abs/10.1021/ja4013535