Huang Group
School of Chemical Biology & Biotechnology

Chengming Wang’s mini-review has been published in Synlett!

时间:2013-04-03

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Expanding Structural Diversity; Removable and Manipulable Directing Groups for C-H Activation

Chengming Wang, Yong Huang*.

Synlett. 201324, 145.(invited)

The need to use a static directing group represents a ­major limitation for the emerging field of ortho-selective C-H ­activation and functionalization. Chemistry was recently developed that allowed partial removal or minor transformations for certain directing groups. Our recent work demonstrated that triazenes were a class of excellent directing groups for C-H activation/functionalization, and subsequent chemical manipulations generated key compounds with synthetic versatility.