Yi Zhang’s work has been published in Org. Biomol. Chem.!

Directed Arenealkyne Annulation Reactions via Aerobic Copper Catalysis

Yi Zhang,a Qian Wang,a Huidong Yu* and Yong Huang*, Org. Biomol. Chem. 2014, 12, 8844-8850

We describe a straightforward protocol for a smooth dehydrogenative annulation reaction between various arenes and terminal alkynes using a catalytic amount of CuBr₂ and molecular oxygen. 3-Methyleneisoindoline derivatives are prepared in high yields.