Huang Group
School of Chemical Biology & Biotechnology

Yi Zhang’s work has been published in Org. Biomol. Chem.!

时间:2014-10-23

Directed Arenealkyne Annulation Reactions via Aerobic Copper Catalysis

Yi Zhang,a Qian Wang,a Huidong Yu* and Yong Huang*, Org. Biomol. Chem. 201412, 8844-8850

We describe a straightforward protocol for a smooth dehydrogenative annulation reaction between various arenes and terminal alkynes using a catalytic amount of CuBr2 and molecular oxygen. 3-Methyleneisoindoline derivatives are prepared in high yields.

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