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The 2017 New Year Party

The 2017 New Year party was held in Shenzhen Jinbaihe Hotel in the evening of January 5, 2017. All the members in our school enjoyed the splendid audio-visual feast! Link: http://scbb.pkusz.edu.cn/index.php?=content&c=index&a=show&catid=862&id=1356

Li group published article on Organic & Biomolecular Chemistry about a study of Improving cell penetration of helical peptides stabilized by N-terminal crosslinked aspartic acids

Cell penetration and nucleus translocation efficiency are important for the cellular activities of peptide therapeutics. For helical peptides stabilized by N-terminal crosslinked aspartic acid, correlations between their penetration efficiency/nucleus translocation and physicochemical properties we...

Li group published article on Organic & Biomolecular Chemistry about a study of Switching substitution groups on the in-tether chiral centre influences backbone peptides’ permeabil...

Different substitution groups on the in-tether chiral centre of chirality-induced helical peptides (CIH peptides) showed distinguishable effects on the peptides’ cellular uptakes and binding affinities with the estrogen receptor α(ER-α). This study proves that in-tether chiral centres are a...

Li group published article on Bioorganic & Medicinal Chemistry about a study of An in-tether sulfoxide chiral center influences the biophysical properties of the N-capped peptides

Li group published article on Bioorganic & Medicinal Chemistry about a study of An in-tether sulfoxide chiral center influences the biophysical properties of the N-capped peptides. Thanks to their large binding interfaces, peptides are attractive ligands targeting protein-protein interactions com...