沈辰

沈辰 Chen Shen

Postdoc（2015~）

Ph.D Shen Zhen Graduate School，Peking University

Mail: shenchen0604@hotmail.com

Education:

2006-2010：BS in chemistry，Yangzhou University

2010-2015：Ph.D, physical chemistry, Peking University

Research Interest:

Structural biology:

Protein-Protein interaction in immune and inflammation pathway.

Structural and functional characterization of disease-related WD40 proteins.

Publications：

Chen Shen, Hong Yue, Jianwen Pei, Xiaomin Guo, Tao Wang*, Junmin Quan* “Crystal structure of the death effector domains of caspase-8” BBRC, 2015, 463, 297–302.

Jun Xu, Chen Shen, Tao Wang*, Junmin Quan* “Structural basis for the inhibition of Polo-like kinase 1” Nat. Struct. Mol. Biol. 2013, 20, 1047-53.

Hong Yue, Feng Lu, Chen Shen, Junmin Quan* “Structure-based design of benzo[e]isoindole-1,3-dione derivatives as selective GSK-3β inhibitors to activate Wnt/β-catenin pathway” Bioorg. Chem. 2015, 61, 21-27.