Zhao Group
School of Chemical Biology & Biotechnology

Jie Rong’s work has been published


Congratulations to Jie Rong for his excellent job accepted by J. Am. Chem. Soc. This work described a chemical approach for direct imaging of newly-synthesized cardiac glycans in rats, based on metabolic labeling with azidosugars followed by chemoselective fluorescence tagging using bioorthogonal chemistry.Their findings demonstrate that sialylation plays an important functional role in mediating hypertrophy progression. The direct visualization of glycans in intact hearts coupled with glycoproteomic analysis is an exciting technical platform that offers a new mechanism for studying how glycosylation regulates the cardiac functions.Hope that he will do better in his reaserch.