深圳市计算化学与药物设计重点实验室
Lab of Computational Chemistry and Drug Design

Zeng Juan

时间:2014-09-26

曾娟

Contact

Email: azengjuan@hotmail.com

 

Education
Ph. D. in Biophysics, 2014, East China Normal University

B. S. in Physics, 2008, Hunan University of Science and Technology

 

Research

1. investigating the effect of polarization for protein.

2. studing the protein interacting with ligand.

3. protein folding.

 

Publications

5. Lu, X. L.; Zeng, J.; Gao, Y.; Zhang, J. Z. H.; Zhang, D. W.; Mei, Y.*, The intrinsic helical propensities of the helical fragments in prion protein under neutral and low pH conditions: A replica exchange molecular dynamics study, Journal of Molecular Modeling, accepted

4. Zeng, J.; Jia, X. Y.; Zhang, J. Z. H.; Mei, Y.*, The F130L mutation in streptavidin reduces its binding affinity to biotin through electronic polarization effect, Journal of Computational Chemistry, accepted
DOI: 10.1002/jcc.23421

3. Zeng, J.; Duan, L. L.; Zhang, J. Z. H.; Mei, Y.*, A numerically stable restrained electrostatic potential charge fitting method, Journal of Computational Chemistry, 34, 847-853 (2013)

2. Ren, S.; Zeng, J.; Mei, Y.; Zhang, J. Z. H.; Yan, S. F.; Fei, J.; Chen, L.*, Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors, Drug Metabolism and Disposition, 41, 60-71 (2013).

1. Mei, Y.*; Li, Y. L.; Zeng, J.; Zhang, J. Z. H.*, Electrostatic polarization is critical for the strong binding in streptavidin-biotin system, Journal of Computational Chemistry, 33, 1374 (2012)