112. Asymmetric Total Synthesis of Lancifodilactone G Acetate

Dong-Dong Liu, Tian-Wen Sun, Kuang-Yu Wang, Yong Lu, Su-Lei Zhang, Yuan-He Li, Yan-Long Jiang, Jia-Hua Chen*, and Zhen Yang*

J. Am. Chem. Soc., 2017, 139,  5732–5735

Asymmetric total synthesis of structurally intriguing and highly oxygenated lancifodilactone G acetate (7) has been achieved for the first time in 28 steps from a cheap commodity chemical, 2-(triisopropylsiloxy)-1,3-butadiene.