127.Diversity-Oriented Synthesis of Natural Products via Gold-Catalyzed Cascade Reactions

Yueqing Gu, Ceheng Tan, Jianxian Gong*, Zhen Yang*

Synlett 2018, 29(12): 1552-1571

This account describes our group’s latest research in the field of diversity-oriented synthesis of natural products via gold-catalyzed cascade reactions. We present two general strategies based on gold-catalyzed cycloisomerization: a gold-catalyzed cascade reaction of 1,7-diynes and a pinacol-terminated gold-catalyzed cascade reaction. We highlight our development of synthetic methods for the construction of biologically active natural products by using these two strategies.