82.Efficient Total Synthesis of Bioactive Natural Products: A Personal Record

Yun Zhang, Jianxian Gong,* and Zhen Yang*

Chem. Rec., 2014, 14, 606

In this account, we have highlighted our most recent works towards the total synthesis of bioactive natural products, which have resulted in the development of several novel synthetic methods. Inspired and guided by strategies based on diversity-oriented synthesis, we have successfully applied the novel synthetic methodologies developed in our lab to the total synthesis of a diverse collection of structurally challenging targets. We have also documented the evolution of these synthetic strategies. The total syntheses described in this account have been organized from the perspective of different molecules whilst still alluding to the parallel synthetic strategies involved.

Chem record