Tao’s work has been published in Organic Letters! Congratulations!
Cheng Tao, Jing Zhang, Xiaoming Chen, Huifei Wang, Yun Li, Bin Cheng, andHongbin Zhai
Org. Lett., 2017, 19, 1056–1059
The tricyclic intermediate 2 has been synthesized in eight steps from known compound 6 in 20% overall yield. As such, this constitutes a highly efficient formal synthesis of (±)-aplykurodinone-1. This synthesis features a unique, one-pot, intramolecular hetero-Pauson-Khand reaction (h-PKR)/desilylation sequence to expeditiously construct the tricyclic framework, providing valuable insights for expanding the scope and boundaries of h-PKR.