赵劲课题组
北京大学深圳研究生院

发表文章

62. Xiong, F.; Lu, L.; Sun, T.-Y.; Wu, Q.; Yan, D.; Chen, Y.; Zhang, X.; Wei, W.; Lu, Y.; Sun, W.-Y.; Li, J. J.; Zhao, J.*, A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis. Nat. Commun. 2017, 8, 15912.

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61. Wu, Q.; Yan, D.; Chen, Y.; Wang, T.; Xiong, F.; Wei, W.; Lu, Y.; Sun, W. Y.; Li, J. J.; Zhao, J.*, A redox-neutral catechol synthesis. Nat. Commun. 2017, 8, 14227.

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60. Wu, Q.; Chen, Y.; Yan, D.; Zhang, M.; Lu, Y.; Sun, W.-Y.; Zhao, J.*, “Unified synthesis of mono/bis-arylated phenols via RhIII-catalyzed dehydrogenative coupling”. Chem. Sci. 2017,8,169-173.

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59. Zhang, L.; Zheng, X. E.; Zou, F.; Shang, Y.; Meng, W.; Lai, E.; Xu, Z.; Liu, Y.; Zhao, J.*, “A highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulphide in living cells and mice”. Sci. Rep. 2016, 6, 18868.

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58. 严义勇,吴谦,陈柱文,杨超,张健,余孟颖,洪梅,赵劲*, “潜在医用气体分子的光学小分子探针” , 中国科学:化学.  2015. 45 (11) :  1145-1158.

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57. Wei, W.; Sun, Y.; Liu, X.; Sun, P.; Wang, F.; Gui, Q.; Meng, W.; Cao, Y.*; Zhao, J.*, “Structural insights and the surprisingly low mechanical stability of the Au-S bond in the gold-specific protein GolB”. J. Am. Chem. Soc. 2015. accepted.

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56. 严义勇, 张玲, 吴谦, 余孟颖, 杨超, 陈柱文, 张健, 赵镜一, 唐红梅, 王双卫, 冯耿超, 魏炜, 洪梅, 赵劲*,“气体信号分子的荧光小分子探针”, 中国科学: 化学. 2015,45(8): 812-828.

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55. Yu, B.; Chen, Y.; Hong, M.; Duan, P.;Gan, S.; Chao, H.* ; Zhao, Z.*; Zhao, J.*,  “Rhodium-Catalyzed C-H Activation of Hydrazines Leads to Isoquinolones with Tunable Aggregation-Induced Emission Property”. Chem. Commun. 2015. online.

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54. Yu, B.; Ouyang, C.; Qiu, K.; Zhao, J.; Ji, L.; Chao, H.*, “Lipophilic Tetranuclear Ruthenium(II) Complexes as Two-Photon Luminescent Tracking Non-Viral Gene Vectors”. Chem. Eur. J.2015, 21 (9), 3691-3700.

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53. Yang, N.; Ding, S.; Chen, F.; Zhang, X.; Xia, Y.; Di, H.; Cao, Q.; Deng, X.; Wu, M.; Wong, C. C. L.; Tian, X.-X.; Yang, C.-G.; Zhao, J.; Lan, L.*, “The Crc protein participates in down-regulation of the Lon gene to promote rhamnolipid production and rhl quorum sensing in Pseudomonas aeruginosa.” Mol. Microbiol. 2015, online.

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52. Yan, L.; Yan, Y.; Pei, L.; Wei, W.*; Zhao, J.*, “A G-quadruplex DNA-based, Label-Free and Ultrasensitive Strategy for microRNA Detection.” Sci. Rep. 2014, 4, 7400,online.

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51.Rong, J.; Han, J.; Dong, L.; Tan, Y.; Yang, H.; Feng, L.; Wang, Q. W.; Meng, R.; Zhao, J.*; Wang, S. Q.*; Chen, X.*, “Glycan Imaging in Intact Rat Hearts and Glycoproteomic Analysis Reveal the Upregulation of Sialylation during Cardiac Hypertrophy.” J. Am. Chem. Soc .2014, 136 (50), 17468–17476.

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50.Yang, M.; Jalloh, A. S.; Wei, W.; Zhao, J.*; Wu, P.*; Chen, P. R.*, “Biocompatible click chemistry enabled compartment-specific pH measurement inside E. coli.” Nature Commun. 2014, 5, 4981-4990.

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49.Zhou, L.; Li, X.; Wang, Y.; Hong, M.*; Liang, Y.*; Zhao, J.*, “Monodisperse, Nanoporous Ceria Microspheres Embedded with Pt Nanoparticles: General Facile Synthesis and Catalytic Application.” RSC Advances 2014, 4, 42965-42970.

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48.Cao, Q.; Wang, Y.; Chen, F.; Xia, Y.; Lou, J.; Zhang, X.; Yang, N.; Sun, X.; Zhang, Q.; Zhuo, C.; Huang, X.; Deng, X.; Yang, C. G.; Ye, Y.; Zhao, J.*; Wu, M.*; Lan, L.*, “A Novel Signal Transduction Pathway that Modulates rhl Quorum Sensing and Bacterial Virulence in Pseudomonas aeruginosa. PLoS pathogens.” 2014, 10 (8), e1004340.

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47.Duan, P.; Lan, X.; Chen, Y.; Qian, S.-S.; Li, J. J.; Lu, L.; Lu, Y.; Chen, B.*; Hong, M.*; Zhao, J.*, “Rhodium(iii)-catalyzed C–H activation/[4+3] annulation of N-phenoxyacetamides and α,β-unsaturated aldehydes: an efficient route to 1,2-oxazepines at room temperature.”Chem. Commun. 2014, 12135–12138.

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46.Chen, Y.; Wang, D.; Duan, P.; Ben, R.; Dai, L.; Shao, X.; Hong, M.; Zhao, J.*; Huang, Y.*, “A multitasking functional group leads to structural diversity using designer C–H activation reaction cascades.” Nature Commun. 2014, 4610-4618.

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45.Zhang, L.; Meng, W.-q.; Lu, L.; Xue, Y.-S.; Li, C.; Zou, F.; Liu, Y.*; Zhao, J.*, “Selective detection of endogenous H2S in living cells and the mouse hippocampus using a ratiometric fluorescent probe.” Sci. Rep2014, 4, 5870-5878.

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44. Yang, H.; Cui, H.; Wang, L.; Yan, L.; Qian, Y.; Zheng, X. E.; Wei, W.*; Zhao, J.*, “A label-free G-quadruplex DNA-based fluorescence method for highly sensitive, direct detection of cisplatin.” Sensor. Actuat. B-Chem. 2014, 202 (0), 714-720.

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43.Zhang, L.; Li, S.; Hong, M.; Xu, Y.; Wang, S.; Liu, Y.*; Qian, Y.*; Zhao, J.*, “A colorimetric and ratiometric fluorescent probe for the imaging of endogenous hydrogen sulphide in living cells and sulphide determination in mouse hippocampus.”, Org. Biomol. Chem. 2014, 12, 5115-5125.

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42.Wei, W.; Liu, X.; Sun, P.; Wang, X.; Hong, Z.; Hong, M.; Mao, Z.-W.*; Zhao, J.*, “Simple Whole-Cell Bio-detection and Bioremediation of Heavy Metals Based on an Engineered Lead-Specific Operon.”, Environ. Sci. Technol. 2014, 48 (6), 3363–3371.

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41.He, J.; Chen, J.; Ren, L.; Wang, Y.*; Teng, C.; Hong, M.; Zhao, J.*; Jiang, B.*, “Fabrication of Monodisperse Porous Zirconia Microspheres and Their Phosphorylation for Friedel-Crafts Alkylation of Indoles.”, ACS Appl. Mater. Interfaces 2014, 6, 2718-2725.

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40.Duan, P.; Yang, Y.-F.; Zhang, X.; Ben, R.; Yan, Y.; Dai, L.; Hong, M.; Wang, D.*; Wu, Y.-D.*; Zhao, J.*, “Palladium-Catalyzed Benzo[d]isoxazole Synthesis by C-H Activation/[4+1] Annulation”, Chem. Sci. 2014, 5, 1574-1578.

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39.Li, G.; Chen, Y.; Wang, J.; Lin, Q.; Zhao, J.; Ji, L.; Chao, H.*, “A dinuclear iridium(iii) complex as a visual specific phosphorescent probe for endogenous sulphite and bisulphite in living cells.”, Chem. Sci. 2013, 4 (12), 4426-4433.

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38.Song, X.; Qian, Y.; Lu, X.;  Zhu, H.-L.; Chao, H.*; Zhao, J.*, “Activation of C–H Bonds in Nitrones Leads to Iridium Hydrides with Antitumor Activity”, J. Med. Chem. 2013,  56, 6531-6535.

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37.Zhou, Y.; Liu, Q.; Lv, W.; Pang, Q.; Ben, R.; Qian, Y.*; Zhao, J.*, “Indazolin-s-ylidene–N-Heterocyclic Carbene Complexes of Rhodium, Palladium, and Gold: Synthesis, Characterization, and Catalytic Hydration of Alkynes”, Organometallics 2013, 32, 3753–3759.

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36.Feng, L.; Hong, S.; Rong, J.; You, Q.; Dai, P.; Huang, R.; Tan, Y.; Hong, W.; Xie, C.*; Zhao, J.*; Chen, X.*, “Bifunctional Unnatural Sialic Acids for Dual Metabolic Labeling of Cell-Surface Sialylated Glycans”,  J. Am. Chem. Soc. 2013, 135, 9244-9247.

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35.Zhao, J.; Lin, S.; Huang, Y.; Zhao, J.* and Chen, P.R.* “Mechanism-based design of a photo-activatable firefly Luciferase”, J. Am. Chem. Soc. 2013, 135, 7410-7413.

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34. Pan, F.; Wang, H.; Shen, P.; Zhao, J. and Shi, Z.* “Cross coupling of thioethers with aryl boroxines to construct biaryls via Rh catalyzed C–S activation”, Chem. Sci.2013, 4, 1573 – 1577.

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33. Feng, L-S; Lv, K; Liu, M-L; Wang, S; Zhao, J; You, X-F; Li,S-J; Cao, J; Guo H-Y. “Synthesis and in vitro antibacterial activity of gemifloxacin derivatives containing a substituted benzyloxime moiety”, Eur. J. Med. Chem., 2012, 55, 125-136.

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32. Lin, R.; Dong, Y.; Liu, J.-X.;* Bai, L.; Gao, J.; Zhu, H.-L.; Zhao, J.* “Inclusion of methylviologen in symmetrical a,a´,d,d´-tetramethyl-cucurbit[6]uril”, RSC Advances, 2012, 2, 7754-7758.

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31. Qian, Y.; Zhang, L.; Ding, S.; Deng, X.; He, C.; Zheng, X.E.; Zhu, H-L; Zhao, J.* “A Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Blood Plasma and Brain Tissues in Mice”, Chem. Sci., 2012, 3(10), 2920-2923.

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30. Wang, Y.; He, J.; Chen, J.; Ren, L.; Jiang, B.*; Zhao, J.*. “Synthesis of Monodisperse, Hierarchically Mesoporous, Silica Microspheres Embedded with Magnetic Nanocrystallites”, ACS Appl. Mater. Interfaces, 2012, 2735-2742.

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29. Wei, W.; Zhu, T.; Wang, Y.; Yang, H.; Hao, Z.; Chen, P.*; Zhao, J.*. “Engineering a Gold-specific Regulon for Cell-based Visual Detection and Recovery of Gold”, Chem. Sci., 2012, 3, 1780-1784.

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28. Gao, W.; He, Z.; Qian, Y.; Zhao, J.*, Huang, Y.* “General Palladium-Catalyzed Aerobic Dehydrogenation to Generate Double Bonds” Chem. Sci., 2012, 3, 883.

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27. Qian, Y.; Karpus, J.; Kabil, O.; Zhu, H-L; Banerjee, R.; Zhao, J.; He, C.* “Selective Fluorescent Probes for Live-Cell Monitoring of Sulfide” Nature Commun., 2011, 2, 1506.

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26. Hou, Y.; Sun, J.; Pang, Z.; Lv, P.; Li, D.; Yan, L.; Zhang, H.; Zheng, E.*; Zhao, J.*; Zhu, H.-L.* “Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors” Bioorg. Med. Chem., 2011, 5948-5954.

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25. Zhang, X.; Chen, D.; Zhao, M.; Zhao, J.*; Jia, A.;* Li, X. * “Synthesis of Isoquinolines via Rhodium(III)-Catalyzed Dehydrative C-C and C-N Coupling between Oximines and Alkynes” Adv. Synth. Catal. 2011, 719-723.

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24. Tao, C.;* Lv, A.; Zhao, N.; Yang, S.; Liu, X.; Zhou, J.; Liu, W.; Zhao, J.* “Ligand-Free Copper-Catalyzed Synthesis of Diaryl Thioethers from Aryl Halides and Thioacetamide” Synlett, 2011, 134-138.

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23. Qian, Y.; Ma, G.; Yang, Y.; Cheng, K.; Zheng, Q.-Z.; Mao, W.-J.; Shi, L.; Zhao, J.*; Zhu, H.-L.* “Synthesis, molecular modeling and biological evaluation of dithiocarbamates as novel antitubulin agents” Bioorg. Med. Chem., 2010, 18, 4310-4316.

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22. Qian, Y.; Zhang, H.; Zhang, H.; Xu, C.*; Zhao, J.*; Zhu, H.-L.* “Synthesis, molecular modeling, and biological evaluation of cinnamic acid metronidazole ester derivatives as novel anticancer agents” Bioorg. Med. Chem., 2010, 18, 4991-4996.

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21. Tao, C.*; Liu, W.; Lv, A.; Sun, M.; Tian, Y.; Wang, Q.; Zhao, J.* “Room-Temperature Copper-Catalyzed Synthesis of Primary Arylamines from Aryl Halides and Aqueous Ammonia” Synlett, 2010, 9, 1355-1358.

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20. Cheng, K.; Zheng, Q.-Z.; Hou, J.; Zhou, Y.; Liu, C.H.; Zhao, J.*; Zhu, H.-L.* “Synthesis, molecular modeling and biological evaluation of PSB as targeted antibiotics” Bioorg. Med. Chem., 2010, 18, 2447-2455.

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19. Qian, Y.; Ma, G.; Lv, A.; Zhu, H.-L.; Zhao, J.*; Rawal, V. H.* “Squaramide-Catalyzed Enantioselective Friedel-Crafts Reaction of Indoles with Imines”, Chem. Comm. 2010, 46, 3004-3006.

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18. Zhao, T. X.; Martinko, A. J.; Le, V. H.; Zhao, J.; Yin, H.* “Development of Agents That Modulate Protein-Protein Interactions in Membranes”, Curr. Pharm. Design, 2010, 16, 1055-1062.

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17. Cheng, K.; Zheng, Q.-Z.; Qian, Y.; Shi, L.; Zhao, J.*; Zhu, H.-L.* “Synthesis, antibacterial activities and molecular docking studies of peptide and Schiff bases as targeted antibiotics” Bioorg.Med.Chem.2009,17,7861-7871.

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16. Li, H.; Shi, L.; Li, Q.; Liu, P.; Luo, Y.; Zhao, J., Zhu, H-L.* “Synthesis of C(7) modified chrysin derivatives designing to inhibit b-ketoacyl-acyl carrier protein synthase III (FabH) as antibiotics”, Bioorg. Med. Chem., 2009, 6264-6269.

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15. Zhou, Y.; Zhao, J.*; Liu, L.* “Meta-selective transition metal-catalyzed arene C-H bond functionalization”, Angew. Chem. Int. Ed. 2009, 7262-7264.

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14. Peng, H.; Zhao, J.*; Li, X.* “Synthesis of trisubstituted pyrroles from rhodium-catalyzed alkyne head-to-tail dimerization and subsequent gold-catalyzed cyclization”, Adv. Synth. Catal. 2009, 1371-1377.

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13. Zhang, Y.; Song, G.; Ma, G.; Zhao, J.*; Pan, C.*; Li, X.* “1,3-Dinitrone pincer complexes of Pd and Ni: synthesis, structural characterizations, and catalysis”, Organometallics. 2009, 3233-3238.

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12. Song, G.; Li, X.*; Song, Z.; Zhao, J.*; Zhang, H.* “Methyleneimidazoline complexes of iridium, rhodium, and palladium from selective C(sp3)-H bond activation”, Chem. Eur. J. 2009, 5535-5544.

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11. Ren, W.; Xia, Y.; Ji, S.; Zhang, Y.; Wan, X.*; Zhao, J. “Wacker-type oxidation of alkynes into 1,2-diketones using molecular oxygen”, Org. Lett. 2009, 1841-1844.

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10. Chen, S.; Li, Y.; Zhao, J.*; Li, X.* “Chelation-assisted carbon-halide bond activation by a rhodium(I) complex”, Inorg. Chem. 2009, 1198-1206.

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9. Panichakul, D.; Su,Y.; Li, Y.; Deng, W.; Zhao, J.*; Li, X.* “A rare h3 binding mode of aryloxides in iridium, rhodium, and ruthenium complexes”, Organometallics. 2008, 6390-6392.

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8. Chen, P.R.; Wasinger, E.C.; Zhao, J.; Greenberg, B.; van der Lelie, D.; Chen, L.; He, C.* “Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR 691” . J. Am. Chem. Soc. 2007, 12350 – 12351.
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7. Zhao, J.; Hughes, O. C.; Toste, F. D. “Synthesis of, aromatic ketones by a transition metal-catalyzed tandem sequence”, J. Am. Chem. Soc. 2006, 128, 7436 – 7437.

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6. Zhao, J.; Hartwig J. F. “Ruthenium-catalyzed dehydrogenation of diols to lactones without solvent and hydrogen acceptors”, Organometallics. 2005, 24, 2441 – 2446.

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5. Zhao, J.; Goldman, A. S; Hartwig J. F. “Oxidative addition of ammonia to form a stable monomeric amido hydride complex”, Science. 2005, 307, 1080 – 1082.

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4. Kanzelberger, M.; Zhang, X.; Emge, T. J.; Goldman, A. S; Zhao, J.; Incarvito, C; Hartwig J. F. “Distinct thermodynamics for the formation and cleavage of N-H bonds in aniline and ammonia. Directly-observed reductive elimination of ammonia from an isolated amido hydride complex”, J. Am. Chem. Soc. 2003, 125, 13644 – 13645.

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3. Zhao, J.; Hesslink, H.; Hartwig, J. F. “Mechanism of b-hydrogen elimination from square planar iridium(I) alkoxide complexes with labile dative ligands”, J. Am. Chem. Soc. 2001, 123, 7220 – 7227.

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2. Zhu, H-L.; Tong, Y-X.; Zhao, J.; Duan, C-Y.; Chen, X-M.; Tang, W-X. “Synthesis,crystal structure and characterization of [bis{N,N’-bis(2-aminoethyl)propane-1,3-diamine} (m-imidazolato-N,N’)dizinc(II)] triperchlorate”, Aust. J. Chem. 1999, 52, 709 – 711.

1. Zhu, H-L.; Hang, Q-W.; Zhao, J.; Duan, C-Y.; Tang, W-X. “The syntheses, crystal structure and magnetic behavior of m-imidazolato-dicopper(II) complexes with the dinucleating hexaazamacrocycles”, Transition Met. Chem., 1999, 23, 131 -134.

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