Our group is interested in a program to develop synthetic strategies and methods with the aim of advancing the frontiers of the total syntheses of biologically important complex natural products. Typical endeavors include 1) exploration of the synthetic strategy of natural product based on photochemical reaction; 2) development of powerful reactions (such as Pauson-Khand reaction and Diels-Alder reaction) for construction of the core structures of biologically important natural products; 3) development of a new synthetic strategy for the semi- synthesis of biologically important natural products from naturally enriched and easily available chiral resources (chiral-pool synthesis).
Since beginning in 2018, my group has made significant progress developing innovative solutions to the synthesis of complex, biologically active natural products and their derivatives. In addition to our strong foundation in target-oriented synthesis, we have become increasingly interested in the biological and drug-discovery oriented natural product research, documented in 54 publications.
Recent and current areas of research
● Synthesis of naturally occurring terpenoids
● Semisynthesis of (−)-anisomelic acid