Z. B. Ma, Z. Xiang, T. P. Luo, K. Lu, Z. Xu, J. H. Chen*, Z. Yang*
J. Comb. Chem., 2006, 8, 696.
Two types of quinoline scaffolds were constructed in a combinatorial format via the Ugi four-component reaction (U-4CR) and Pd-catalyzed intramolecular arylation reaction. The scope of this two-step synthetic sequence was examined from commercially available and synthetically accessible starting materials.
