Publications

24.An Efficient One-Pot Asymmetric Synthesis of Biaryl Compounds via Diels-Alder/Retro-Diels-Alder Cascade Reactions

   

Y. X. Liu, K. Lu, M. J. Dai, K. Wang, W. Wu, J. H. Chen*, Z. Yang*

Org. Lett., 2007, 9, 805.

A single-step chirality transfer method for the synthesis of axially chiral biaryl compounds by construction of the second aromatic ring via a Diels−Alder/retro-Diels−Alder cascade reaction is reported. This methodology should find broad application in the synthesis of natural products and asymmetric catalysts.

*This publication was highlighted on http://www.organic-chemistry.org/Highlights/2007/08October.shtm