Dr. Hao Wei, Chuang Qiao, Gang Liu, Prof. Dr. Zhen Yang, Prof. Dr. Chuang-chuang Li
Angew. Chem. Int. Ed. 2013, 52, 2, 620
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Convergent approach: The total syntheses of (−)-flueggine A and (+)-virosaine B (see scheme) have been accomplished in a concise and convergent manner. Key steps in these approaches were relay ring-closing metathesis reactions for rapid construction of the key intermediates, and 1,3-dipolar cycloaddition reactions for the formation of the natural products.