Y. Liang, L. Wang, R. Zhu, L. J. Deng, Y. Yang, J. M. Quan, J. H. Chen*, Z. Yang*
Adv. Synth. Catal. 2010, 352, 2387.
Silver hexafluroantimonate was identified as a highly efficient agent to reverse the facial selectivity of the titanium chloride-mediated vinylogous Mukaiyama aldol reaction (VMAR), and this unprecedented reaction provides a concise, diastereoselective synthesis of δ-hydroxy-α,γ-dimethyl-α,β-unsaturated carbonyl units from readily available chiral vinylketene silyl N,O-acetal 6 and ethyl glyoxylate 8.
