A Norrish-Yang photocyclization reaction has been applied to regio- and stereoselective construction of the ABCDE pentacyclic motif of natural product phainanoids. The observed substrate conformation control implicates this powerful reaction could be applied to the construction of structurally diverse natural product scaffolds.
Yi-Ke Zhou, Zhen-Yu Zhang, Hao-Yuan Liu, Yuan-He Li, Zhong-Chao Zhang, Jia-Hua Chen*, Zhen Yang*
Org. Lett. 2024, 26, 8217–8221.
A Norrish-Yang photocyclization reaction has been applied to regio- and stereoselective construction of the ABCDE pentacyclic motif of natural product phainanoids. The observed substrate conformation control implicates this powerful reaction could be applied to the construction of structurally diverse natural product scaffolds.
