Publications

177.Synthesis of Poly-substituted 2-Hydroxycyclobutanones via Norrish–Yang Photocyclization/1,2-Methyl Migration: Scope and limitations

Fu Tang, Zhongchao Zhang*, Zhen Yang*

Tetrahedron Lett. 2024, 145, 155161.

Poly-substituted 2-hydroxycyclobutanone motifs are core motifs in many biologically important natural products, we recently developed Norrish–Yang photocyclization/1,2-methyl migration as a synthetic strategy for regio/stereoselectively constructing them and profiled the scope and limitations of the proposed strategy in this work.