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于海昕

   

于海昕

Haixin YU

College of Chemistry and Molecular Engineering

Peking University

202 Chengfu Road

Beijing 100871, China

Tel: 86–17701380102

E-mail: haixinyu@pku.edu.com

 

Education

2013.9 – 2019.7   Ph.D., Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Study, Peking University, Beijing, China.

Research projects: total syntheses of Schisandra nortriterpenoids natural products propindiactone G, 19-dO-arisandilactone A, pre-schisanartanin C.

Supervisor: Prof. Zhen Yang, Prof. Jiahua Chen.

2011.8 – 2013.7   M.S., As a joint training graduate students, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.

Research projects: total syntheses of anticancer natural product fusarisetin A and analogues; studies toward total syntheses of indole terpenoids of xiamycin, indosespene, oridamycin A and B, dixiamycin.A .

Supervisor: Prof. Ang Li.

2010.9 – 2013.7 M.S., candidate, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University. Shenyang, China.

Supervisor: Prof. Jing Han.

2004.9 – 2008.7 B.S., School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, China.

Professional Experience

2008.8 – 2010.6 Research assistant, Jinzhou AHON Pharmaceutical CO.Ltd, Jinzhou, China.

 

Skills

Skilled in preparative synthetic techniques from ~2 mg to multi-gram scale. Competent in the preparation, handling and storage of air and moisture sensitive reagents using inert atmosphere and Schlenk techniques. Accomplished use of NMR spectroscopy.

 

Publications

  1. Liang, X.-T.; You, L.; Li, Y.-H.; Yu, H.-X.; Chen, J. H, Zhen Yang, Z.“Asymmetric Total Synthesis of Propindilactone G, Part 3: The Final Phase and Completion of the Synthesis”, Asian J. 2016, 11, 1425.

  2. Han, -X.; Jiang, Y.-L.; Li, Y.; Yu, H.-X.; Tong, B.-Q.; Niu, Z.; Zhou, S.-J.; Liu, S.; Lan, Y.; Chen, J.-H.; Yang, Z. “Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A” Nat. Commun.2017, 8, 14233.

  3. Deng, B. Zhu, Z. Lu, H. Yu, A. Li. Total Synthesis of (–)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart, J. Am. Chem. Soc. 2012, 134, 920–923.

  4. Z. Meng, Yu,L. Li, W. Tao, H. Chen, M. Wan, P. Yang, D. J. Edmonds, J. Zhong, A. Li. “Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families” Nat. Commun. 2014, 6, 6096.