郑楠
Nan Zheng, Ph. D.
Education & Experience
2020-now Research Associate, Peking University.
2017-2020 Postdoctoral Research Associate, University of Utah & Stanford University, Mentor: Prof. Danny Chou & Prof. J. Michael McIntosh.
2012-2017 Ph.D.in Chemical Genetics, Peking University, Mentor: Prof. Zhen Yang.
2008-2012 B.S. in Pharmacy, Sichuan University, Advisor: Prof. Jinsong Yang.
Awards & Honors
2019 Excellent Poster Award of 14th Annual Peptide Therapeutics Symposium
2019 American Diabetes Association (ADA) Postdoctoral Fellowship
2017 Merit Student of Peking University
2017 Morningside Excellent Research Article Scholarship
2016 May 4th Scholarship of Peking University
2012 Excellent Graduate Student of Sichuan University
Research Interests
Protein Engineering, Peptide Chemistry, Medicinal Chemistry, Organic Synthesis.
Publications
1.Nan Zheng, Sean B. Christensen, Alan Blakely, Cheryl Dowell, Landa Purushottam, J. Michael McIntosh and Danny Hung-Chieh Chou. Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors. J. Med. Chem. 2020, doi.org/10.1021/acs.jmedchem.0c00613.
2.Nan Zheng, Prasoona Karra, Michael A. VandenBerg, Jin Hwan Kim, Matthew J. Webber, William L. Holland and Danny Hung-Chieh Chou. Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analogue with Enhanced Stability. J. Med. Chem. 2019, 62, 11437-11443.
3.Nan Zheng, Lijie Zhang, Jianxian Gong and Zhen Yang. Formal Total Synthesis of (±)-Lycojaponicumin C. Org. Lett. 2017, 19, 2921-2924.
4.Nan Zheng, Yuan-Yuan Chang, Li-Jie Zhang, Jian-Xian Gong and Zhen Yang. Gold-Catalyzed Intramolecular Tandem Cyclization of Indole-Ynamides: Diastereoselective Synthesis of Spirocyclic Pyrrolidinoindolines. Chem. Asian J. 2016, 11, 371-375.
5.Yibo Qiu,+ Rahul Agrawal,+ Diao Chen, Nan Zheng, Griffin Durupt, Jin Hwan Kim, Simon J. Fisher and Danny Hung-Chieh Chou. Long-Lasting Designer Insulin with Glucose-Dependent Solubility Markedly Reduces Risk of Hypoglycemia. Adv. Therap. 2019, 2, 1900128.
6.Linlin Shi, Yingdong He, Yuanyuan Chang, Nan Zheng, Zhen Yang and Jianxian Gong. Stereoselective Pd-Catalyzed Decarboxylative Allylation: Assembly of Highly Functionalized Allylic Amines Bearing a Quaternary Center. Org. Lett. 2019, 21, 3077-3080.
