News&Event
Congratulation to Jingjie Li for her review paper was published on Synthesis!
Congratulation to Jingjie Li for her paper has been published on Synthesis！ This review titled “Thioureas as Ligands in Organometallic Reactions”, . For more details, please see the paper online:
https://web.pkusz.edu.cn/yang/81/
or
Li’s page: https://web.pkusz.edu.cn/yang/lijingj/
81.Thioureas as Ligands in Organometallic Reactions
Jingjie Li, Li-Li Shi, Jiahua Chen, Jianxian Gong, Zhen Yang*
Thioureas are air and moisture stable, and they can coordinate to various metal centers, making their derivatives versatile ligands for transition-metal-catalyzed reactions. This account provides an overview of recent developments in the use of thioureas as ligands in organometallic-catalyzed reactions, with particular emphasis on their application to the total synthesis of natural products.
Guozong Yue and Lily Shi have successfully defended their dissertations
Guozong Yue and Lily Shi have successfully defended their dissertations and shall be conferred the doctor’s degree. Congratulations!
Congratulation to Yun Zhang for her review paper was published on NPR!
Congratulation to Yun Zhang for her paper has been published on Natural Product Reports！ This review titled “Strategic innovation in the total synthesis of complex natural products using gold catalysis”. For more details, please see the paper online:
https://web.pkusz.edu.cn/yang/79/
or
Nat. Prod. Rep., 2014, 31, 489
Zhang’s page: https://web.pkusz.edu.cn/yang/zhangy/
80.Strategic innovation in the total synthesis of complex natural products using gold catalysis
Yun Zhang, Tuoping Luo* and Zhen Yang*
Nat. Prod. Rep., 2014, 31, 489
Novel organic reactions drive the advance of chemical synthesis in the same way that enabling technologies drive new scientific discoveries. One area of organic methodology that has undergone significant growth during the last decade is that of homogeneous gold-catalyzed transformations. This trend has been further enhanced by the employment of gold catalysis on a routine basis to accomplish the total synthesis of natural products. In particular, the superior π acidity of the cationic gold complex for the activation of alkynes and allenes towards nucleophilic addition has significantly enriched the toolkit of transformations available to the total synthesis community, and inspired a new era of creativity in terms of the strategic disconnection of target compounds during their retrosynthetic analysis. Instead of simply supplementing the many existing reviews of gold catalysis, this review has been organized from the perspective of synthetic target families, with particular emphasis on the use of gold-catalyzed transformations during the late stages of syntheses involving complicated substrates, and cascade reactions that significantly increase molecular complexity.
