Molecular Cell Biology Lab

Lu Fei’s resume

时间:2014-07-31

 

2

number:18028703548

 

E-mail: mrslufei@gmail.com, lufei@pkusz.edu.cn

Current Address: Peking University Campus Building F Room 406, Nanshan District Xili University Town, Shenzhen, Guangdong, China, 518055

 

Education:

Sept. 1989 - July 1993:         Bachelor Degree (B. S.)

Department of Biology

Xijiang Normal University,

Xinjiang, China.

Sept. 2002 - July 2008:         Ph. D. Degree

College of Life Sciences,

Peking University,

Beijing, China

 

Career:

Sept. 2011- present      Associate professor

Peking University Shenzhen Graduate School, Shenzhen, China

Specialize in mechanism of epigenetic regulation by histone methylation and acetylation, Stem cell     differentiation,      WD40 repeat protein function, regulation of DNA replication and DNA damage check point

 

Dec. 2008- July 2011         Postdoctoral fellow

Nevada Cancer Institute, Las Vegas, Nevada, USA

Dr. Hui Zhang as supervisor

Majoring in epigenetic regulation of DNA replication and transcription, CUL4-DDB1-WD40 ubiquitin E3 ligases, DNA damage checkpoint control, CUL4 and WDR5 knockout mice. Skilled in ES cell and IPS cell culture, embryonic cell isolation, molecular and cell biology techniques, and animal analysis.

July 2002 - July 2008:     Ph. D. student in College of Life      Sciences, Peking University, Beijing, China

Dr. Chuanmao Zhang as supervisor

Majoring in regulation of DNA replication initiation regulation (the function of Cdt1, Geminin and Cdc6 on DNA replication and centrosomal duplication) and skilled in cellullar and molecular biology techniques, including tissue culture, immunofluorescence microscopy, molecular cloning, biochemistry of kinase analysis, time-laps microscopy imaging of live cell and immunoprecipitation assays, etc.

March 2009- present:      Associate Professor in Department of Cell Biology and Genetics

Shihezi University Medical School

Xinjiang, China

June 1993-March 2009:    Lecturer in Department of Cell Biology and Genetics Shihezi University Medical School Xinjiang, China

 

Bibliography:

 

1) Rongfeng Lan, Guimiao Lin, Feng Yin, Jun Xu, Xiaoming Zhang, Jing Wang, Yanchao Wang, Jianxian Gong, Yuan-Hua Ding, Zhen Yang, Fei Lu* and Hui Zhang. (2012) Dissecting the Phenotypes of Plk1 Inhibition in Cancer Cells Using Novel Kinase Inhibitory Chemical CBB2001. Laboratory Investigation (2012), 1-C12. *Co-corresponding author.

 

2) Jing Wang, Fei Lu*, Qi Ren, Hong SunZhengshuang Xu, Rongfeng Lan, Yuqing Liu, David Ward, Junmin Quan, Tao Ye,, and Hui Zhang (2011). Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties. Cancer Res 71:7238-7249. *Co-first author.

 

3) Fei Lu, Rongfeng Lan, Hongyin Zhang, Qing Jiang and Chuanmao Zhang. Geminin is partially localized to centrosome and plays a role in proper centrosome duplication. (2009) Biol. Cell 101, 273-C285.

 

4) Fei Lu, Rongfeng Lan, Xuelong LV, Qing Jiang, Hui Zhang and Chuanmao Zhang.  Phosphorylation of Geminin by CDK2 Regulates its Interaction with Cdt1 and Assembly of pre-RC in Mitosis. (2007) The American Society for Cell Biology 47th Annual Meeting Program, 126.

 

5) Fei Lu, Chuanmao Zhang: The regulation of initiation of DNA replication,-Molecular and Cellular biology-Edit by Yeguang Chen, Chuanmao Zhang and Quan Chen-Beijing, Tsinghua University Publication, 2006.9; 245-260.

 

6) Xiaofeng Zheng, Xueyu Dai, Yanmei Zhao, Qiang Chen, Fei Lu, Deqiang Yao, Quan Yu, Xinping Liu, Chuanmao Zhang, Xiaocheng Gu, and Ming Luo. Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. (2007) Proc. Natl. Acad. Sci. USA 104(21): 8809-C8814.

 

7)Hui Ren, Liya Wang, Matthew Bennett, Yuhe Liang, Xiaofeng Zheng, Fei Lu, Lanfen Li, Jie Nan, Ming Luo,Staffan Eriksson, Chuanmao Zhang, and Xiao-Dong Su. The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus. (2005) Proc. Natl. Acad. Sci. USA, 102(2): 303-C308.

 

8) Fei Lu, Christina Lee, Ivailo Mihalov, and Hui Zhang. (2012) Regulation of DNA Re-replication and Chromosomal Polyploidy by MLL-WDR5-RBBP5 Methyltransferase Complexes. EMBO Report, submitted, under review.