Publications after 2014 (in Shenzhen)
2019
| 22. Lee HC, Zhao YJ. Resolving the topological enigma in Ca2+-signaling by cyclic ADP-ribose and NAADP. J Biol Chem. 2019 Dec 27;294(52):19831-19843. |
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| 21. Zhao ZY, Xie XJ, Li WH, Liu J, Chen Z, Zhang B, Li T, Li SL, Lu JG, Zhang L, Zhang LH, Xu Z, Lee HC*, Zhao YJ*. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. iScience. 2019 May 31;15:452-466. |
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| 20. Deng QW, Zhang J, Li T, He WM, Fang L, Lee HC, Zhao YJ. The transferrin receptor CD71 regulates type II CD38, revealing tight topological compartmentalization of intracellular cyclic ADP-ribose production. J Biol Chem. 2019 Oct 18;294(42):15293-15303. |
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| 19. Wu Y, Zhang J, Fang L, Lee HC*, Zhao YJ*. A cytosolic chaperone complex controls folding and degradation of type III CD38. J Biol Chem. 2019 Mar 15;294(11):4247-4258 |
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| 18. Yang L#, Li T#, Li S, Wu Y, Shi X, Jin H, Liu Z, Zhao Y*, Zhang L*, Lee HC, Zhang L. (2019). Rational Design and Identification of Small-Molecule Allosteric Inhibitors of CD38. Chembiochem. 2019 Oct 1;20(19):2485-2493.
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201900169 |
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| 17. Yu P, Liu Z, Yu X, Ye P, Liu H, Xue X, Yang L, Li Z, Wu Y, Fang C, Zhao YJ, Yang F, Luo JH, Jiang LH, Zhang L, Zhang L, Yang W. Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket. Cell Rep. 2019 Jun 18;27(12):3684-3695
https://www.sciencedirect.com/science/article/pii/S2211124719306965 |
| 16. Gao B, Chen S, Hou YN, Zhao YJ, Ye T, Xu Z. Solution-phase total synthesis of teixobactin. Org Biomol Chem. 2019 Jan 31;17(5):1141-1153.
https://pubs.rsc.org/en/content/articlelanding/2019/ob/c8ob02803f#! |
2018
| 15. An N*, Hou YN*, Zhang QX, Li T, Zhang QL, Fang C, Chen H, Lee H, Zhao Y&, Du X&. Anti-Multiple Myeloma Activity of Nanobody-Based Anti-CD38 Chimeric Antigen Receptor T Cells. Mol Pharm. 2018 Oct 1;15(10):4577-4588 |
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| 14. Li T, Li SL, Fang C, Hou YN, Zhang Q, Du X, Lee HC*, Zhao YJ*. Nanobody-based dual epitopes protein identification (DepID) assay for measuring soluble CD38 in plasma of multiple myeloma patients. Anal Chim Acta. 2018 Oct 31;1029:65-71
https://www.sciencedirect.com/science/article/pii/S0003267018305476 |
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| 13. Fang C, Li T, Li Y, Xu GJ, Deng QW, Chen YJ, Hou YN, Lee HC*, Zhao YJ*. CD38 produces nicotinic acid adenosine dinucleotide phosphate in the lysosome. J Biol Chem. 2018 May 25;293(21):8151-8160. |
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| 12. Jiang Y, Deng Q, Zhao H, Xie M, Chen L, Yin F, Qin X, Zheng W, Zhao Y*, Li Z*. Development of Stabilized Peptide-Based PROTACs against Estrogen Receptor α. ACS Chem Biol. 2018 Mar 16;13(3):628-635 |
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2017
| 11. Liu J*, Zhao YJ*&, Li WH, Hou YN, Li T, Zhao ZY, Fang C, Li SL, Lee HC&. Cytosolic interaction of type III human CD38 with CIB1 modulates cellular cyclic ADP-ribose levels. Proc Natl Acad Sci U S A. 2017, 114(31):8283–8288. |
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| 10. Boslett J, Hemann C, Zhao YJ, Lee HC, Zweier JL. Luteolinidin protects the post-ischemic heart through CD38 inhibition with preservation of NAD(P)(H). J Pharmacol Exp Ther. 2017 Apr;361(1):99-108. |
| 9. Fumey W, Koenigsdorf J, Kunick V, Menzel S, Schütze K, Unger M, Schriewer L, Haag F, Adam G, Oberle A, Binder M, Fliegert R, Guse A, Zhao YJ, Cheung Lee H, Malavasi F, Goldbaum F, van Hegelsom R, Stortelers C, Bannas P, Koch-Nolte F. Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo. Sci Rep. 2017 Oct 30;7(1):14289. |
2016
| 8. Li T, Qi S, Unger M, Hou YN, Deng QW, Liu J, Lam MC, Wang XW, Du X, Zhang P, Koch-Nolte F, Hao Q, Zhang HM*, Lee HC*, Zhao YJ*. Immuno-targeting the multifunctional CD38 using nanobody. Scientific Reports. 2016 Jun 2;6:27055 |
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| 7. Zhong J, Amina S, Liang M, Akther S, Yuhi T, Nishimura T, Tsuji C, Tsuji T, Liu HX, Hashii M, Furuhara K, Yokoyama S, Yamamoto Y, Okamoto H, Zhao YJ, Lee HC, Tominaga M, Lopatina O, Higashida H. Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice. Front Neurosci. 2016 Jul 22;10:304. |
2015
| 6. Zhao YJ, Zhu WJ, Wang XW, Zhang LH, Lee HC. Determinants of the membrane orientation of a calcium signaling enzyme CD38. Biochim Biophys Acta-Molecular Cell Research. 2015 Sep;1853(9):2095-103. F1000Prime RECOMMENDEDhttps://www.sciencedirect.com/science/article/pii/S0167488914003875 |
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| 5. Davidson SM, Foote K, Kunuthur S, Gosain R, Tan N, Tyser R, Zhao YJ, Graeff R, Ganesan A, Duchen MR, Patel S, Yellon DM. Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore. Cardiovasc Res. 2015 Sep 22. pii: cvv226.
https://academic.oup.com/cardiovascres/article/108/3/357/557223 |
| 4. Li N, Zhu WJ, Xue XW, Zhao YJ, Lee HC, Zhang L, Zhang L. The synthesis of purine derivatives and its inhibitory activity on CD38 NADase. Acta Pharmaceutica Sinica, 2015, 50(8): 1013-1020. |
| 3. Li J, Pei F, Zhu W, Jin H, Zhao Y, Zhang L, Lee H, Zhang L. Investigation of the effect of 2’substitution of NMN analogues on CD38 NADase inhibitory activity. Journal of Chinese Pharmaceutical Sciences. 2015, 24(8): 514-523. |
2014
| 2. Wang S, Zhu W, Wang X, Li J, Zhang K, Zhang L, Zhao YJ, Lee HC, Zhang L. Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase. Molecules. 2014 Sep 29;19(10):15754-67. |
| 1. Lee HC and Zhao YJ. The Type III calcium signaling mechanism of CD38. Messenger 2014, 3, 59-64.
https://www.researchgate.net/publication/277089941_The_type_III_calcium_signaling_mechanism_of_CD38 |
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