Publications-YANG Group

39. Unexpected Regioselectivity in the Synthesis of Pyranonaphthoquinone via the Diels−Alder Reaction

Y. Cui, H. Jiang, Z. T. Li, N. Wu, Z. Yang* and J. M. Quan* Org. Lett. 2009, 11, 4628. The unusual regioselectivity in the Diels−Alder reactions of pyranoquinone 1 with (4,4-dimethoxybuta-1,3-dien-2-...

38.Formal Total Synthesis of N-Methylmaysenine

L. Wang, J. X. Gong, L. J. Deng, Z. Xiang, Z. X. Chen, Y. Wang, J. H. Chen*, Z. Yang* Org. Lett. 2009, 11, 1809. A novel synthetic approach for the formal total synthesis of N-methylmaysenine (1) has ...

37.Characterization and Development of Novel Small-Molecules Inhibiting GSK3 and Activating Wnt Signalling

H. B. Zhong, H. X. Zou, M. V. Semenov, D. Moshinsky, X. He, H. Huang, S. Li, J. M. Quan, Z. Yang, S. Lin* Mol. BioSyst. 2009, 5, 1356. Glycogen synthase kinase 3 (GSK3) is an essential component of th...

36.Identifying Tumor Cell Growth Inhibitors by Combinatorial Chemistry and Zebrafish Assays

J. Xiang, H. B. Yang, C, Che, H. X. Zou, H. B. Yang, Y. Wei, J. M. H. Zhang*, Z. Yang, S. Lin* PLoS One 2009, 4, e4361. Cyclin-dependent kinases (CDKs) play important roles in regulating cell cycle pr...

35. Pincer Thioamide and Pincer Thioimide Palladium Complexes Catalyze Highly Efficient Negishi Coupling of Primary and Secondary Alkyl Zinc Reagents at Room Temperature

H. B. Wang, J. Liu, Y. Deng, T. Y. Min, G. X. Yu, X. J. Xu, Z. Yang, A. W. Lei* Chem. Eur. J. 2009, 15, 1499-1507. Pincer thioamide PdII complex 2 was prepared, and its reaction with cyclohexylzinc ch...

34.A model study for the concise construction of the oxapentacyclic core of cortistatins through intramolecular Diels-Alder and oxidative dearomatization-cyclization reactions

L. Z. Liu, Y. X. Gao, C. Che, N. Wu, D. Z. Wang, C. C. Li*, Z. Yang* Chem. Commun., 2009, 662-664. A unified strategy towards the facile construction of the [6.7.6.5] oxapentacyclic skeleton of co...

33.Synthesis of Catechins via Thiourea/AuCl3-Catalyzed Cycloalkylation of Aryl Epoxides

Y. X. Liu, X. Li, G. Li, Z. Xiang, J. Xiang, M. Z. Zhao, J. Chen*, Z. Yang* J. Org. Chem. 2008, 73, 4625. A diversity-oriented approach for the synthesis of structurally diverse catechins was achieved...

32.Total Synthesis of Crisamicin A

Z. T. Li, Y. X. Gao, Y. F. Tang, M. J. Dai, G. X. Wang, Z. G. Wang* and Z. Yang* Org. Lett., 2008, 10, 3017. Stereoselective total synthesis of natural product crisamicin A (1) was accomplished for ...

31.Diversity-Oriented Synthesis of Fused Pyran v-Lactones via an Efficient Pd−Thiourea-Catalyzed Alkoxycarbonylative Annulation

Z. T. Li, Y. X. Gao, Z. D. Jiao, N. Wu, D. Z. G. Wang* and Z. Yang* Org. Lett. 2008, 10, 5163. We reported herein a diversity-oriented synthesis of a range of fused pyran-γ-lactones that was effected...

30. Steteoselective Construction of an Unprecedented 7-8 Fused Ring System in Micrandilactone A by [3,3]-Sigmatropic Rearrangement

Y. D. Zhang, W. Ren, Y. Lan, Q. Xiao, K. Wang, J. Xu, J. H. Chen*, Z. Yang* Org. Lett. 2008, 10, 665. The 7−8 bicyclic ring system of micrandilactone A (1) with the required stereochemistry and funct...