On June 26，2016, with the invitation of Prof. Zigang Li，Prof. Jiang Xia, Prof. Liming Bian meet in Shenzhen and Hongkong Forum and gave an interesting seminar about chemical biology, students of our groups actively participated in the academic discussion and...
On October 22, 2016, we attended the Protein Folding Shape Alignment （PFSA）Meeting in Wuhan, students of our groups actively participated in the academic discussion and exchanged ideas.
A very nice trip in guilin, guangxi province, besides we had academic exchange with the students and teachers from Guangxi Normal University.
On November 3, 2016, we attended the 2016 World Life Science Conference in Beijing, students of our groups actively participated in the academic discussion and exchanged ideas. <a
On November 4, 2016, with the invitation of Prof. Zigang Li, engineer Shuiming Li visited our school and gave an interesting lecture titled “Applications of modern mass spectrometry technology ”, teachers and students of our school actively participated in...
On November 8，2016, with the invitation of Prof. Zigang Li, teachers and students of our school actively participated in the academic discussion and exchanged ideas. Protein-ligand interactions mediated by modular domains, which often play important roles in regulating cellular...
Lanthanide chelate-encapsulated polystyrene nanoparticles for rapid and quantitative immunochromatographic assay of procalcitonin Procalcitonin (PCT) is a potentially specific early marker of bloodstream infection and sepsis. In this work, we report, for the first time, the development of a fluorescence-based...
On November 9，2016, with the invitation of Prof. Zigang Li，Prof. Yongye Liang visited our school and gave an interesting lecture about biomaterial, students of our school actively participated in the academic discussion and exchanged ideas.
Our lab member Huacan Lin won the third place of 2016 “Freshman Cup” badminton game
Our lab member Weirong Qin won the third place of 2016 “Freshman Cup” table tennis game
Li group published article on Bioconjugate Chemistry about a study of Investigation of Cellular Uptakes of the In-Tether Chiral-CenterInduced Helical Pentapeptides We recently reported that a precisely positioned in-tether chiral center can modulate backbone peptides’ secondary structures, which provides an...
Li group published article on Bioorganic & Medicinal Chemistry about a study of An in-tether sulfoxide chiral center influences the biophysical properties of the N-capped peptides. Thanks to their large binding interfaces, peptides are attractive ligands targeting protein-protein interactions compared...
nducing α-helicity through side-chain cross-linking is a strategy that has been pursued to improve peptide conformational rigidity and bio-availability. Here we describe the preparation of small peptides tethered to chiral sulfoxide-containing macrocyclic rings. Furthermore, a study of structure-activity relationships...
Different substitution groups on the in-tether chiral centre of chirality-induced helical peptides (CIH peptides) showed distinguishable effects on the peptides’ cellular uptakes and binding affinities with the estrogen receptor α(ER-α). This study proves that in-tether chiral centres are a...
Cell penetration and nucleus translocation efficiency are important for the cellular activities of peptide therapeutics. For helical peptides stabilized by N-terminal crosslinked aspartic acid, correlations between their penetration efficiency/nucleus translocation and physicochemical properties were studied. An increase in hydrophobicity...